<p>Lipid class composition (graph A) on left side) and phosphatidylcholine species composition (graph B) on right side) are indicated as means for each diagnosis. The number of subjects is detailed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0117985#pone.0117985.t001" target="_blank">Table 1</a>. The numbers above the columns indicate the mean phospholipid concentrations (μmol/l). No statistical comparisons were done; the graphical display should allow a rapid identification of deviations from the controls. The other species are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0117985#pone.0117985.s004" target="_blank">S4 Fig</a>. Only lipid species present at an abundance of > 0...
BACKGROUND: Lipids account for the majority of pulmonary surfactant, which is essential for normal b...
The bar graphs represent log2(fold change) in the respective ratios relative to PBS controls to dete...
In the score plot (left panel, for annotations see Fig 1) samples are color-coded by disease categor...
<p>A) Phosphatidylcholine, the major surfactant phospholipid class and B) its species dipalmitoylpho...
<p>Lipid class composition is expressed as % of the analyzed displayed lipid classes (left graph). B...
Fifteen phospholipids with the highest discriminatory power between the disease categories are prese...
<p>Individual lipids from different lipid classes are shown: (A) lysophosphatidyl choline, (B) sphin...
<p>All analyzed lipids are the sum of all analyzed phospholipid classes, cholesteryl ester and free ...
Rationale: Pulmonary alveolar proteinosis (PAP) is characterized by filling of the alveolar spaces b...
<p>Figures in brackets denote percentage composition in alveolar PL (data from <a href="http://www.p...
<p>(<b>A</b>) mol% lipid category. Notice that the y-axis is logarithmic. Data is displayed as the a...
<p>Tab. f6 –PCA loadings of the four lipidomes from ATGL-study: The columns indicate the principal c...
<p>(A) Saturated phosphatidylcholine (Sat PC µmol/kg) in CHF5633 (Input), Survanta (Input), lamb lun...
<p>A bar graph of the number of differentially abundant lipids (paired t test, p-value < 0.05, FDR <...
Lipids account for the majority of pulmonary surfactant, which is essential for normal breathing. We...
BACKGROUND: Lipids account for the majority of pulmonary surfactant, which is essential for normal b...
The bar graphs represent log2(fold change) in the respective ratios relative to PBS controls to dete...
In the score plot (left panel, for annotations see Fig 1) samples are color-coded by disease categor...
<p>A) Phosphatidylcholine, the major surfactant phospholipid class and B) its species dipalmitoylpho...
<p>Lipid class composition is expressed as % of the analyzed displayed lipid classes (left graph). B...
Fifteen phospholipids with the highest discriminatory power between the disease categories are prese...
<p>Individual lipids from different lipid classes are shown: (A) lysophosphatidyl choline, (B) sphin...
<p>All analyzed lipids are the sum of all analyzed phospholipid classes, cholesteryl ester and free ...
Rationale: Pulmonary alveolar proteinosis (PAP) is characterized by filling of the alveolar spaces b...
<p>Figures in brackets denote percentage composition in alveolar PL (data from <a href="http://www.p...
<p>(<b>A</b>) mol% lipid category. Notice that the y-axis is logarithmic. Data is displayed as the a...
<p>Tab. f6 –PCA loadings of the four lipidomes from ATGL-study: The columns indicate the principal c...
<p>(A) Saturated phosphatidylcholine (Sat PC µmol/kg) in CHF5633 (Input), Survanta (Input), lamb lun...
<p>A bar graph of the number of differentially abundant lipids (paired t test, p-value < 0.05, FDR <...
Lipids account for the majority of pulmonary surfactant, which is essential for normal breathing. We...
BACKGROUND: Lipids account for the majority of pulmonary surfactant, which is essential for normal b...
The bar graphs represent log2(fold change) in the respective ratios relative to PBS controls to dete...
In the score plot (left panel, for annotations see Fig 1) samples are color-coded by disease categor...